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Table 2 Cohorts 7–9 – Adjuvant disease cohorts and defined standard of care ICI-containing treatment regimens

From: The MITRE trial protocol: a study to evaluate the microbiome as a biomarker of efficacy and toxicity in cancer patients receiving immune checkpoint inhibitor therapy

Cohort

Disease

Regimen

Primary outcome measure

Cohort 7

Resected AJCC stage 3 or 4 melanoma

Anti-PD-1 monotherapy (nivolumab or pembrolizumab)

1 year & 2 year RFS

Cohort 8

Resected renal cancer

Durvalumab

1 year & 2 year RFS

Cohort 9

Resected renal cancer

Durvalumab+tremelimumab

1 year & 2 year RFS