Table 1 Categorical and continuous variables of patients with different numbers of NLN
Right side colon, n = 891 | Left side colon, n = 1353 | |||
|---|---|---|---|---|
Categorical variables | NLN ≥ 27 n = 499 (100%) | NLN <  27 n = 392(100%) | NLN ≥ 12 n = 1020 (100%) | NLN <  12 n = 333 (100%) |
Sex, P-value | 0.069 | 0.254 | ||
 Male | 219 (43.9) | 196 (50.0) | 530 (52.0) | 185 (55.6) |
 Female | 280 (56.1) | 196 (50.0) | 490 (48.0) | 148 (44.4) |
Age, P-value | 0.001 | 0.002 | ||
 Mean, SD (years) | 62.2, ±13.5 | 65.2, ±13.6 | 61.5, ±13.4 | 64.1, ±12.8 |
Age groups, P-value | 0.004 | 0.010 | ||
 < 50 year-old | 86 (17.2) | 53 (13.5) | 185 (18.1) | 44 (13.2) |
 50–65 year-old | 188 (37.7) | 115 (29.3) | 408 (40.0) | 116 (34.8) |
 65–80 year-old | 177 (35.5) | 171 (43.6) | 339 (33.2) | 140 (42.0) |
 ≥80 year-old | 48 (9.6) | 53 (13.5) | 88 (8.6) | 33 (9.9) |
BMIa, P-value | 0.184 | 0.226 | ||
 Mean, SD | 23.6, ±3.6 | 23.9,±3.9 | 24.2, ±3.7 | 24.5,±3.7 |
BMI groupsa, P-value | 0.379 | 0.706 | ||
 Underweight (BMI < 18.5) | 31 (6.2) | 24 (6.3) | 45 (4.5) | 11 (3.4) |
 Normal weight (18.5≦BMI <  24) | 260 (52.3) | 182 (47.8) | 460 (45.5) | 142 (44.0) |
 Overweight (24≦BMI <  27) | 117 (23.5) | 109 (28.6) | 292 (28.9) | 94 (29.1) |
 Obesity (BMI≧27) | 89 (17.9) | 66 (17.3) | 214 (21.2) | 76 (23.5) |
Pre-OP CEAa, P-value | 0.566 | 0.715 | ||
 Mean, SD (ng/mL) | 11.2, ±24.5 | 12.3, ±31.5 | 8.7, ±20.4 | 9.1, ±19.0 |
CEA groups, P-value | 0.459 | 0.054 | ||
 ≥5 ng/mL | 181 (37.0) | 150 (39.5) | 339 (33.5) | 128 (39.4) |
 < 5 ng/mL | 308 (63.0) | 230 (60.5) | 672 (66.5) | 197 (60.6) |
Pre-OP NLR, P-value | 0.219 | 0.007 | ||
 Mean, SD | 3.3, ±2.8 | 3.6, ±3.9 | 2.8, ±2.1 | 3.3, ±3.8 |
NLR,P-value | 0.650 | 0.060 | ||
 ≥2.87 | 200 (43.7) | 143 (42.1) | 284 (30.7) | 100 (36.8) |
 < 2.87 | 258 (56.3) | 197(57.9) | 641 (69.3) | 172 (63.2) |
Histology type, P-value | 0.389 | 0.019 | ||
 Adenocarcinoma | 427 (85.6) | 341 (87.0) | 966 (94.7) | 307 (92.2) |
 Signet ring cell | 11 (2.2) | 4 (1.0) | 5 (0.5) | 7 (2.1) |
 Mucinous | 61 (12.2) | 47 (12.0) | 49 (4.8) | 19 (5.7) |
Histology grade, P-value | 0.028 | 0.771 | ||
 Well differentiation | 28 (5.6) | 41 (10.5) | 83 (8.1) | 29 (8.7) |
 Moderate differentiation | 379 (76.1) | 284 (72.4) | 872 (85.6) | 279 (84.0) |
 Poorly differentiation | 91 (18.3) | 67 (17.1) | 64 (6.3) | 24 (7.2) |
T stage of TNM, P-value | < 0.001 | < 0.001 | ||
 T1 | 14 (2.8) | 1 (0.3) | 40 (3.9) | 17 (5.1) |
 T2 | 17 (3.4) | 17 (4.3) | 80 (7.8) | 36 (10.8) |
 T3 | 293 (58.7) | 179 (45.7) | 594 (58.2) | 140 (42.0) |
 T4 | 175 (35.1) | 195 (49.7) | 306 (30.0) | 140 (42.0) |
N stage of TNM, P-value | 0.019 | 0.004 | ||
 N1 | 349 (70.1) | 245(62.5) | 697(68.3) | 199(59.8) |
 N2 | 150 (29.9) | 147 (37.5) | 323 (31.7) | 134 (40.2) |
 Stage III, P-value | 0.045 | < 0.001 | ||
 IIIA | 32 (5.8) | 13 (3.9) | 105 (10.3) | 42 (12.6) |
 IIIB | 409 (73.6) | 225 (67.2) | 720 (70.6) | 195 (58.6) |
 IIIC | 115 (20.7) | 97 (29) | 195 (19.1) | 96 (28.8) |
Adjuvant C/T, P-value | < 0.001 | 0.001 | ||
 Yes | 446 (85.4) | 242 (74.7) | 807 (82.9) | 247 (74.6) |
 No | 76 (14.6) | 82 (25.3) | 166 (17.1) | 84 (25.4) |
ELN, P-value | < 0.001 | < 0.001 | ||
 Mean, SD | 46.5, ±15.2 | 20.6, ±6.5 | 30.2, ±13.9 | 11.4, ±4.3 |
ELN group, P-value | < 0.001 | < 0.001 | ||
 ≥12 | 556 (100.0) | 300 (89.6) | 1020 (100.0) | 248 (74.5) |
PLN, P-value | 0.002 | < 0.001 | ||
 Mean, SD | 3.2, ±3.4 | 4.0, ±4.3 | 3.3, ±3.4 | 4.2, ±4.1 |
NLN, P-value | < 0.001 | <  0.001 | ||
 Mean, SD | 43.3, ±14.8 | 16.6, ±6.0 | 26.9, ±13.6 | 7.2, ±2.9 |