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Fig. 5 | BMC Cancer

Fig. 5

From: Iodine-125 seed represses the growth and facilitates the apoptosis of colorectal cancer cells by suppressing the methylation of miR-615 promoter

Fig. 5

125I seed inhibited the growth of CRC cells in vivo by activating miR-615 expression. A Images of tumors in each group. B Tumor growth curve. C Tumor weight. D The methylation level of miR-615 in tumors was detected using MSP. E miR-615 expression of cells in each group was detected using RT-qPCR. F The expression of Ki67 was detected using immunohistochemistry. G Apoptosis of tissues in each group was detected using TUNEL. N = 3. The cell experiments were repeated 3 times independently. Data are presented as mean ± standard deviation. Data were analyzed using one-way ANOVA, followed by Tukey’s multiple comparisons test. *p < 0.05 vs. the control group; #p < 0.05 vs. the 125I group

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