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Fig. 1 | BMC Cancer

Fig. 1

From: Somatic mutations in collagens are associated with a distinct tumor environment and overall survival in gastric cancer

Fig. 1

Collagens are significantly mutated in stomach adenocarcinoma in the TCGA dataset. A. Distribution of alteration frequencies for collagen genes (orange) compared to all other genes (blue) in the TCGA STAD cohort. P-value determined by Wilcoxon rank test comparing the distribution of collagen genes relative to all other genes. B. Alteration frequencies for each collagen gene in all TCGA STAD cases. C. and in MSS, MSIH, and MSIL STAD cases. D. Kolmogorov-Smirnov moderated tests suggest that collagen genes as a group are significantly mutated compared to gene sets of similar size and length in the whole TCGA STAD cohort and in both MSS and MSIH tumors

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BMC Cancer

ISSN: 1471-2407

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