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Table 1 Association between clinical data and NLR/PLR

From: Significance of the neutrophil-to-lymphocyte ratio in predicting the response to neoadjuvant chemotherapy in extremity osteosarcoma: a multicentre retrospective study

clinical parameters

n

NLR

PLR

LNLR

(n = 50)

HNLR

(n = 46)

p-value

LPLR

(n = 30)

HPLR

(n = 66)

p-value

Age (year)

   

0.447

  

0.823

  ≤ 17

56

31

25

 

18

38

 

  > 17

40

19

21

 

12

28

 

Sex

   

0.959

  

0.165

 Male

54

28

26

 

20

34

 

 Female

42

22

20

 

10

32

 

Tumor location

   

0.949

  

0.363

 Tibia

40

28

12

 

16

24

 

 Femur

44

30

14

 

10

34

 

 Others

12

8

4

 

4

8

 

Tumor size (cm3)

195.37 ± 8.74

171.37 ± 12.94

218.34 ± 11.24

0.034

173.22 ± 10.54

201.97 ± 15.24

0.041

Enneking stage

   

0.024

  

0.321

 I

28

18

10

 

10

18

 

 II

46

26

20

 

16

30

 

 III

22

6

16

 

4

18

 

Subtype

   

0.202

  

0.362

 Osteoblastic

58

34

24

 

15

43

 

 Chondroblastic

22

8

14

 

9

13

 

 Others

16

8

8

 

6

10

 

ALP

   

0.013

  

0.763

 Elevated

50

20

30

 

16

34

 

 Normal

46

30

16

 

14

32

 

ESR

   

0.478

  

0.352

 Elevated

70

38

32

 

20

50

 

 Normal

26

12

14

 

10

16

 

CRP

   

0.148

  

0.161

 Elevated

64

38

26

 

17

47

 

 Normal

32

14

18

 

13

19

 

Mononuclear(109/L)

0.64 ± 0.28

0.58 ± 0.23

0.66 ± 0.29

0.376

0.64 ± 0.20

0.65 ± 0.31

0.782