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Table 4 Logistic regression analyses of Odds ratio (OR) for CIN2+ vs ≤ CIN1 according to multiple vs. single HPV infection

From: Roles of extended human papillomavirus genotyping and multiple infections in early detection of cervical precancer and cancer and HPV vaccination

hrHPV types Single infection Multiple infection OR (95% CI) P-value††
No. CIN2+/ total No. CIN2+/ total
16 194/667 85/353 0.8 (0.6-1.1) 0.144
18 16/230 0/35 NA NA
31 15/88 3/39 0.4 (0.1-1.4) 0.132
33 23/71 5/48 0.2 (0.1-0.6) 0.004
35 8/38 2/21 0.5 (0.1-3.2) 0.462
39 0/85 0/0 NA NA
45 1/23 0/9 NA NA
51 3/121 2/10 11.0 (1.5-80.6) 0.018
52 13/199 2/71 0.4 (0.1-1.9) 0.248
56 1/58 4/26 6.5 (0.4-99.4) 0.180
58 26/193 20/99 1.6 (0.8-3.1) 0.178
59 2/43 0/13 NA NA
66 3/67 1/7 4.9 (0.4-64.6) 0.224
68 3/97 5/24 8.8 (1.8-43.8) 0.008
  1. The analysis was adjusted for age. ††P-values from multiple comparisons were corrected at a Bonferroni threshold (P = 0.05/14 = 0.0036)
  2. Abbreviations: CI confidence interval, CIN2+ cervical intraepithelial neoplasia 2 or worse, OR odds ratio, NA not available