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Table 3 Cumulative PPV/Sensitivity/Specificity (%) for CIN3+ in the triage of hrHPV-positive women

From: Roles of extended human papillomavirus genotyping and multiple infections in early detection of cervical precancer and cancer and HPV vaccination

hrHPV types

Primary type

For the new type

Cumulative types

PPV (%)

CIN3+/HPV+

PPV (%)

CIN3+/HPV+

PPV (%)

SEN (%)

SPE (%)

16

18.0

184/1020

18.0

184/1020

18.0

73.3

66.3

33

15.3

17/119

14.3

201/1139

17.6

80.1

62.2

31

8.2

11/127

8.7

212/1266

16.7

84.5

57.6

58

8.5

21/292

7.2

233/1558

15.0

92.8

46.7

45

8.8

1/32

3.1

234/1590

14.7

93.2

45.4

66

2.8

2/74

2.7

236/1664

14.2

94.0

42.5

52

6.0

6/270

2.2

242/1934

12.5

96.4

31.9

18

3.5

5/265

1.9

247/2199

11.2

98.4

21.4

35

7.1

1/59

1.7

248/2258

11.0

98.8

19.1

56

4.5

1/84

1.2

249/2342

10.6

99.2

15.7

51

1.7

1/131

0.8

250/2473

10.2

99.6

10.5

68

4.0

1/121

0.8

251/2594

9.7

100.0

5.7

59

1.0

0/56

0.0

251/2650

9.5

100.0

3.4

39

2.2

0/85

0.0

251/2735

9.2

100.0

0.0

  1. Abbreviations: CIN3+ cervical intraepithelial neoplasia 3 or worse, SEN sensitivity, SPE specificity, PPV positive predictive value