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Table 3 Cumulative PPV/Sensitivity/Specificity (%) for CIN3+ in the triage of hrHPV-positive women

From: Roles of extended human papillomavirus genotyping and multiple infections in early detection of cervical precancer and cancer and HPV vaccination

hrHPV types Primary type For the new type Cumulative types
PPV (%) CIN3+/HPV+ PPV (%) CIN3+/HPV+ PPV (%) SEN (%) SPE (%)
16 18.0 184/1020 18.0 184/1020 18.0 73.3 66.3
33 15.3 17/119 14.3 201/1139 17.6 80.1 62.2
31 8.2 11/127 8.7 212/1266 16.7 84.5 57.6
58 8.5 21/292 7.2 233/1558 15.0 92.8 46.7
45 8.8 1/32 3.1 234/1590 14.7 93.2 45.4
66 2.8 2/74 2.7 236/1664 14.2 94.0 42.5
52 6.0 6/270 2.2 242/1934 12.5 96.4 31.9
18 3.5 5/265 1.9 247/2199 11.2 98.4 21.4
35 7.1 1/59 1.7 248/2258 11.0 98.8 19.1
56 4.5 1/84 1.2 249/2342 10.6 99.2 15.7
51 1.7 1/131 0.8 250/2473 10.2 99.6 10.5
68 4.0 1/121 0.8 251/2594 9.7 100.0 5.7
59 1.0 0/56 0.0 251/2650 9.5 100.0 3.4
39 2.2 0/85 0.0 251/2735 9.2 100.0 0.0
  1. Abbreviations: CIN3+ cervical intraepithelial neoplasia 3 or worse, SEN sensitivity, SPE specificity, PPV positive predictive value