Skip to main content

Table 3 Response rate to different lines of chemotherapy based on BRCA status

From: Assessing frequency and clinical outcomes of BRCA mutated ovarian cancer in Saudi women

Best Response First line (n = 61) Second line (n = 49) Third line (n = 39) Fourth line (n = 23)
BRCAm
n = 25
BRCAw
n = 36
BRCAm
n = 18
BRCAw
n = 31
BRCAm
n = 13
BRCAw
n = 26
BRCAm
n = 10
BRCAw
n = 13
CR 92% 72.7% 50% 29% 46.2% 7.7% 20% 7.7%
PR 8% 27.3% 44.4% 35.5% 38.5% 19.2% 20% 7.7%
SD 5.6% 9.7% 26.9% 10% 15.4%
PD 25.8 15.4% 34.6% 50% 38.5%
NA 3 patients 3 patients 4 patients
ORR 100% 100% 94.4% 64.5% 84.7% 30.6% 40% 22.2%
P-Value*   0.01 0.002 0.40
  1. * Chi-square or Fisher’s exact test; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; NA, not available; ORR, objective response rate