Table 2 Association of NSAID use with risk of death due to suicide or accident after cancer diagnosis, a cohort study of 388,443 cancer patients diagnosed between Oct 2005 and Dec 2014 in Sweden
From: NSAID use and unnatural deaths after cancer diagnosis: a nationwide cohort study in Sweden
Characteristics | Completed suicide | Death due to accident | ||||
|---|---|---|---|---|---|---|
N | Crude IR (per 1000 person-years) | HR (95% CI) | N | Crude IR (per 1000 person-years) | HR (95% CI) | |
Low-dose aspirin | ||||||
Off medication (Ref) a | 228 | 0.23 | 1.0 | 1627 | 1.63 | 1.0 |
On medication b | 59 | 0.25 | 0.92 (0.64–1.31) | 651 | 2.80 | 0.88 (0.80–0.98) |
As above + cancer stage, cancer type and Chronic Disease Score | – | – | 1.01 (0.69–1.47) | – | – | 0.79 (0.71–0.88) |
As above + history of psychiatric disorders | – | – | 0.96 (0.66–1.39) | – | – | 0.78 (0.70–0.87) |
Non-aspirin NSAIDs | ||||||
Off medication (Ref) a | 274 | 0.02 | 1.0 | 2219 | 0.15 | 1.0 |
On medication b | 13 | 0.03 | 1.02 (0.45–2.32) | 59 | 0.13 | 0.96 (0.71–1.30) |
As above + cancer stage, cancer type and Chronic Disease Score | – | – | 1.01 (0.44–2.32) | – | – | 0.92 (0.68–1.25) |
As above + history of psychiatric disorders | – | – | 0.95 (0.42–2.18) | – | – | 0.92 (0.68–1.25) |