Variables | n = 58 |
---|---|
No. (%) | |
Sex | |
Male | 45 (78%) |
Female | 13 (22%) |
Age (years) (Median, Range) | 66 (38–82) |
ECOG performance status | |
0 | 8 (14%) |
1 | 36 (62%) |
2 | 12 (21%) |
3 | 2 (3%) |
Disease status | |
Metastatic | 43 (74%) |
Relapsed | 15 (26%) |
Primary site | |
Gastric | 49 (84%) |
Esophagogastric junction | 9 (16%) |
Histological type | |
Intestinal type | 34 (59%) |
Diffuse type | 24 (41%) |
HER-2 status | |
Positive | 13 (22%) |
Site of metastases | |
Lymph nodes | 41 (72%) |
Peritoneum | 27 (47%) |
Liver | 20 (34%) |
Lung | 12 (21%) |
Bone | 9 (16%) |
Other | 7 (12%) |
Organs with metastasis | |
1 | 17 (29%) |
2 | 24 (42%) |
3 | 13 (22%) |
≥ 4 | 4 (7%) |
Previous treatment regimens | |
2 | 35 (60%) |
3 | 18 (31%) |
≥ 4 | 5 (9%) |
Previous therapies | |
Pyrimidine analogs | 56 (97%) |
Platinum | 50 (86%) |
Taxane | 55 (95%) |
Ramucirumab | 48 (83%) |
Trastuzumab | 11 (19%) |
Irinotecan | 16 (28%) |
Treatment period before nivolumab (months) | 14.9 (4.9–64.6) |
Immune-related adverse events | |
Positive | 10 (17%) |