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Table 5 Results of univariate and multivariate analysis of clinicopathological factors affecting RFS

From: Prognostic value of preoperative high-sensitivity modified Glasgow prognostic score in advanced colon cancer: a retrospective observational study

 

variable

univariate analysis

multivariate analysis

 

HS-GPS model

GPS model

mGPS model

p value

HR

95%CI

p value

HR

95%CI

p value

HR

95%CI

p value

Age

(years)

0.027

1.349

0.897–2.028

0.151

1.281

0.848–1.934

0.24

1.232

0.830–1.830

0.3

< 75

          

≥75

          

Sex

 

0.545

         

female

          

male

          

BMI

 

0.174

         

≥18.5

          

< 18.5

          

tumor location

 

0.912

         

right side

          

left side

          

operation approach

 

0.078

         

open

          

lap

          

Tumor size

(cm)

0.086

         

< 5

          

≥5

          

T

 

< 0.001

1.571

0.777–3.179

0.209

1.572

0.78–3.618

0.206

1.555

0.802–3.014

0.191

T2/3

          

T4

          

N

 

0.001

2.747

1.797–4.199

< 0.001

2.549

1684–3.857

< 0.001

2.55

1.715–3.793

< 0.001

N0

          

N1/2/3

          

CEA

(ng/ml)

< 0.001

2.093

1.420–3.086

< 0.001

2.093

1.420–3.086

< 0.001

1.998

1.376–2.902

< 0.001

< 5

          

≥5

          

CA19–9

(U/ml)

0.064

         

< 37

          

≥37

          

HS-GPS

0

reference

         

1

0.693

         

2

0.051

         

GPS

0

reference

         

1

0.798

         

2

0.011

   

1.537

1.190–1.987

0.002

   

mGPS

0

reference

         

1

0.203

         

2

0.007

      

1555

1.206–2.005

0.004

  1. Abbreviation: HS-GPS high sensivity modified-Glasgow Prognostic Score, GPS Glasgow Prognostic Score, m-GPS modified-GPS, BMI body mass index, CEA carcinoembryonic antigen, CA19–9 carbohydrate antigen 19–9
  2. P-values <0.05 were considered to indicate statistical significance
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BMC Cancer

ISSN: 1471-2407

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