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Table 4 Results of univariate and multivariate analysis of clinicopathological factors affecting OS

From: Prognostic value of preoperative high-sensitivity modified Glasgow prognostic score in advanced colon cancer: a retrospective observational study

 

variable

univariate analysis

multivariate analysis

 

HS-GPS model

GPS model

mGPS model

p value

HR

95%CI

p value

HR

95%CI

p value

HR

95%CI

p value

Age

(years)

0.001

2.049

1.195–3.413

0.009

2.052

1.180–3.568

0.11

1.98

1.163–3.371

0.02

< 75

          

≥75

          

Sex

 

0.764

         

female

          

male

          

BMI

 

0.035

0.562

0.300–1.054

0.072

0.502

0.270–1.003

0.051

0.601

0.321–1.125

0.111

≥18.5

          

< 18.5

          

tumor location

 

0.725

         

right side

          

left side

          

operation approach

 

0.895

         

open

          

lap

          

Tumor size

(cm)

0.344

         

< 5

          

≥5

          

T

 

< 0.001

2.254

1.272–3.992

0.005

2.381

1.315–4.311

0.004

1.955

1.090–3.508

0.025

T2/3

          

T4

          

N

 

0.001

1.925

1.081–3.429

0.026

2.014

1.016–3.670

0.022

2.04

1.157–3.598

0.014

N0

          

N1/2/3

          

CEA

(ng/ml)

0.019

1.547

0.894–2.674

0.119

1.583

0.913–2.746

1.102

1.601

0.941–2.721

0.082

< 5

          

≥5

          

CA19–9

(U/ml)

0.038

1.238

0.630–2.611

0.493

0.906

0.421–1.948

0.8

1.13

0.561–2.276

0.733

< 37

          

≥37

          

HS-GPS

0

reference

         

1

0.265

         

2

0.012

2.638

1.046–6.650

0.04

      

GPS

0

reference

         

1

0.633

         

2

0.001

   

1.444

1.018–2.048

0.04

   

mGPS

0

reference

         

1

0.805

         

2

0.001

      

1.51

1.066–2.140

0.02

  1. Abbreviation: HS-GPS high sensivity modified-Glasgow Prognostic Score, GPS Glasgow Prognostic Score, m-GPS modified-GPS, BMI body mass index, CEA carcinoembryonic antigen, CA19–9 carbohydrate antigen 19–9
  2. P-values < 0.05 were considered to indicate statistical significance
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BMC Cancer

ISSN: 1471-2407

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