Fig. 5From: Digital gene expression analysis of NSCLC-patients reveals strong immune pressure, resulting in an immune escape under immunotherapyDifferential expression of genes in association with T cell receptor signaling. The plots were created via the pathview package in R. Red:Â Genes are expressed in association with a specific escape mechanism. Green: Genes are expressed without an escape mechanism being present. Grey: Genes are expressed indifferent of any escape mechanism. A KEGG pathway analysis of T cell receptor signaling in patients expressing PD-L1. B KEGG pathway analysis of T cell receptor signaling in patients showing signs of altered epitope processing (discovery cohort). C KEGG pathway analysis of T cell receptor signaling in patients showing signs of altered epitope processing (validation cohort). D KEGG pathway analysis of T cell receptor signaling in patients showing signs of altered epitope processing and high levels of PD-L1 expressionBack to article page