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Fig. 4 | BMC Cancer

Fig. 4

From: Digital gene expression analysis of NSCLC-patients reveals strong immune pressure, resulting in an immune escape under immunotherapy

Fig. 4

Differential gene expression in natural killer cell mediated cytotoxicity. The plots were created via the pathview package in R. Red: Genes are expressed in association with a specific escape mechanism. Green: Genes are expressed without an escape mechanism being present. Grey: Genes are expressed indifferent of any escape mechanism. A KEGG pathway analysis of natural killer cell mediated cytotoxicity in patient expressing PD-L1. B KEGG pathway analysis of natural killer cell mediated cytotoxicity in patient showing signs of altered epitope processing (discovery cohort). C KEGG pathway analysis of natural killer cell mediated cytotoxicity in patients showing signs of altered epitope processing (validation cohort). D KEGG pathway analysis of natural killer cell mediated cytotoxicity in patients showing signs of altered epitope processing and PD-L1 expression

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BMC Cancer

ISSN: 1471-2407

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