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Table 3 Presence, copy number and Ct values of bacteria in normal and tumor tissues

From: High frequency of enterotoxigenic Bacteroides fragilis and Enterococcus faecalis in the paraffin-embedded tissues of Iranian colorectal cancer patients

 

CRC (n = 40)

Control (n = 40)

P value

Qualitative presentation, percent patients positive a

   

Fusobacterium spp

   

Yes

27 (67.5%)

24 (60%)

0.48

No

13 (32.5%)

16 (40%)

 

ETBF

   

Yes

18 (45%)

6 (15%)

0.003

No

22 (55%)

34 (85%)

 

S. gallolyticus

   

Yes

29 (72.5%)

28 (70%)

0.80

No

11 (27.5%)

12 (30%)

 

E. faecalis

   

Yes

34 (85%)

25 (62.5%)

0.005

No

6 (15%)

15 (37.5%)

 

Range and median values of Ct

   

Fusobacterium spp

25.8–38.3 (30.7)

25.3–39.1 (31.3)

> 0.05

ETBF

23.4–38.2 (37.5)

26.9–39.1 (38.8)

> 0.05

S. gallolyticus

26.4–36.8 (31.2)

28.1–37.8 (31.8)

> 0.05

E. faecalis

21.5–37 (28.3)

23.3–38.1 (29.7)

> 0.05

Log copies DNA ml−1 b

   

Fusobacterium spp

2.9 ± 0.32

2.8 ± 0.15

0.23

ETBF

3.81 ± 0.07

2.7 ± 0.63

0.002

S. gallolyticus

3.04 ± 0.12

2.98 ± 0.31

0.39

E. faecalis

4.4 ± 0.10

3.1 ± 0.43

0.001

  1. aValues noted as number (percentage), Fisher’s exact test
  2. bValues noted as log copies DNA ml−1, Mann–Whitney test