| Excluded from the study N(%) | Included in the study N(%) | P-value | NSCLC N (%) | SCLC N(%) |
---|---|---|---|---|---|
Total number of patients | 2,263 (31) | 6,210 (69) | Â | 5,320 (100) | 890 (100) |
ECOG PS, N(%) | |||||
 0 | 784 (35) | 1,946 (31) |  < 0.0001 | 1,733 (33) | 213 (24) |
 1 | 749 (33) | 1,894 (31) | 1,610 (30) | 284 (32) | |
 2 | 257 (11) | 820 (13) | 672 (13) | 148 (17) | |
 3 | 297 (13) | 854 (14) | 704 (13) | 150 (17) | |
 NA | 176 (8) | 696 (11) | 601 (11) | 95 (10) | |
 Age, years median (range 5%—95%) | 70 (53 – 85) | 70 (52 – 84) | 0.06 | 70 (52 – 84) | 69 (52–83) |
Sex | |||||
 Female | 1,120 (49) | 3,014 (49) | 0.44 | 2,556 (48) | 456 (51) |
 Male | 1,143 (51) | 3,196 (51) |  | 2,762 (52) | 434 (49) |
Stage | |||||
 I | 479 (21) | 1,188 (19) |  < 0.0001 | 1,142 (21) | 46 (5) |
 II | 117 (5) | 531 (9) | 508 (10) | 23 (3) | |
 III | 453 (20) | 1,167 (19) | 943 (18) | 224 (25) | |
 IV | 1,057 (47) | 2,807 (45) | 2,291 (43) | 518 (58) | |
 NA | 107 (5) | 517 (8) | 436 (8) | 79 (9) | |
Histology | |||||
 Adenocarcinoma | 1,084 (48) | 2,769 (45) | 0.24 | 2,769 (52) |  |
 SCC | 481 (21) | 1,281 (21) | 1,281 (24) |  | |
 Other | 193 (9) | 674 (11) | 674 (13) |  | |
 NSCLCa | 194 (9) | 596 (10) | 596 (11) |  | |
 SCLC | 311 (14) | 890 (14) |  | 890 (100) | |
Smoking | |||||
 Never Ever NA | 114 (5) 1,716 (76) 433 (19) | 237 (4) 4,562 (73) 1,411 (23) |  < 0.0001 | 230 (4) 3,899 (73) 1,191 (22) | 7 (1) 663 (74) 220 (25) |