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Table 1 Demographic and clinical characteristics of 44 patients with multiple myeloma, stratified by anti-SARS-CoV-2 RBD antibody response to two-dose SARS-CoV-2 mRNA vaccination

From: Safety and antibody response to two-dose SARS-CoV-2 messenger RNA vaccination in patients with multiple myeloma

 

Overall (n = 44)

Detectable antibodya (n = 41)

Undetectable antibodya (n = 3)

Age, median (IQR)

64 (57, 69)

64 (57, 69)

58 (55, 58)

Female, no. (%)

30 (68)

28 (93)

2 (7)

Non-white, no. (%)

1 (2)

1 (100)

0 (0)

Vaccine manufacturer, no. (%)

 Pfizer/BioNTech

22 (50)

21 (95)

1 (5)

 Moderna

22 (50)

20 (91)

2 (9)

Days from vaccine to antibody testing, median (IQR)

29 (28, 32)

29 (27, 31)

32 (28, 38)

Therapy, no. (%)

 Not on therapy

17 (39)

16 (94)

1 (6)

 On therapyb

27 (61)

25 (93)

2 (7)

  Bortezomib

1 (2)

1 (100)

0 (0)

  Carfilzomib

1 (2)

1 (100)

0 (0)

  Daratumumab

7 (16)

7 (100)

0 (0)

  Ixazomib

2 (5)

1 (50)

1 (50)

  Lenalidomide

17 (39)

16 (94)

1 (6)

  Pomalidomide

4 (9)

4 (100)

0 (0)

  Teclistamab

1 (2)

0 (0)

1 (100)

  1. a The percentages in these columns are shown as percent of each category in the overall column. Detectable antibody is defined as an anti-SARS-CoV-2 RBD antibody titer > 0.79 U/mL by the manufacturer
  2. b Since participants could report more than one therapy, the sum of the therapies is greater than the total N