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Fig. 3 | BMC Cancer

Fig. 3

From: The opposing action of stromal cell proenkephalin and stem cell transcription factors in prostate cancer differentiation

Fig. 3

Reversal of reprogramming by PENK. The top row of photomicrographs (magnification 100x) show the cell appearance of LNCaP vs. LNCaP* vs. LNCaP*/PENK. The electropherogram confirms the downregulation of SOX2 in LNCaP*/PENK. The neo signal provides sample loading control. The gel picture is composed of two halves of a single run (bottom and top rows of wells with different background staining intensity). The bottom row of photomicrographs (magnification 200x) show a direct comparison of the colony morphology between neoRbsrR LNCaP*/PENK and neoR LNCaP/PENK

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