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Fig. 2 | BMC Cancer

Fig. 2

From: The opposing action of stromal cell proenkephalin and stem cell transcription factors in prostate cancer differentiation

Fig. 2

a. Gene expression changes induced by PENK in LuCaP 145.1. The electropherogram shows expression analysis displaying downregulation of scTF and upregulation of B2M in PENK-transfected LuCaP 145.1 (PENK+) as gauged from the intensities of the reaction products in comparison to the corresponding ones seen in α-scTF-transfected LuCaP 145.1 (PENK–). POU5F1 was not as strongly affected. The gel picture is a composite of two halves of a single run (bottom and top rows of wells with different background ethidium bromide staining). b. B2M levels. The histogram is generated from dataset query of transcriptomes for signal intensity values (y-axis) of the genes listed in the various cell types identified on the x-axis. The red lines highlight the B2M expression levels in stem cell types – B2Mlo vs. differentiated cell types – B2Mhi

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