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Table 1 Patient demographics and disease characteristics (n = 228)

From: Neoadjuvant chemotherapy and radiotherapy followed by resection/ablation in stage IV rectal cancer patients with potentially resectable metastases

Characteristics

No. of patients (%) b

Age at start of treatment a (years)

56 (25–81)

Sex ratio (M: F)

160: 68

KPS

 70–80

26 (11.4)

 90–100

202 (88.6)

Clinical tumor category

 T2 N1–2

2 (0.9)

 T3 N0

2 (0.9)

 T3 N1–2

95 (41.7)

 T4 N1–2

129 (56.6)

Metastatic site

 Liver

116 (50.9)

 Lung

64 (28.1)

 Liver and lung

20 (8.8)

 Distant lymph nodes

28 (12.3)

No. of liver metastases

n = 116

 1–3

78 (67.2)

 4–5

9 (7.8)

 ≥ 6

29 (25)

Location of liver metastases

n = 136

 Unilobar

52 (38.2)

 Multilobar

84 (61.8)

Diameter of largest liver metastasis a (cm)

2.0 (0.6–12)

Length of rectal cancer a (cm)

5.5 (1.5–16)

Location of primary rectal cancer

 Low (0-5 cm)

61 (26.8)

 Middle (5-10 cm)

134 (58.8)

 High (10-15 cm)

33 (14.5)

Differentiation

 Well

9 (3.9)

 Moderate

177 (77.6)

 Poor

31 (13.6)

 Unknown

11 (4.8)

CEA at diagnosis a (ng/ml)

14.6 (0.7–2677)

CA199 at diagnosis a (U/ml)

31.4 (0.6–20,000)

  1. a Values are median (range). bWith percentages in parentheses unless indicated otherwise
  2. Abbreviations: KPS Karnofsky Performance Status, CEA carcinoembryonic antigen, CA199 carbohydrate antigen 19–9