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Fig. 5 | BMC Cancer

Fig. 5

From: Identification of an at-risk subpopulation with high immune infiltration based on the peroxisome pathway and TIM3 in colorectal cancer

Fig. 5

Comparison of tumor mutational burden and possible sensitivity to immunotherapy for CRC subgroups. a Top 20 genes most frequently mutated in TCGA CRC patients in groups I + II, III, and IV. b Comparison of the tumor mutation load across the three CRC subgroups in TCGA. c Plots show immune checkpoint genes of the three CRC subgroups in TCGA. d The same as panel c, but for the GSE39582 cohort. e Heatmaps show the correlation between transcriptomic expression patterns of melanoma patients receiving PD1 or CTLA4 inhibitors and CRC subgroups in TCGA. f The same as panel e, but for the GSE39582 dataset. ***P < 0.001

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BMC Cancer

ISSN: 1471-2407

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