Skip to main content
Fig. 4 | BMC Cancer

Fig. 4

From: Landscape of homologous recombination deficiencies in solid tumours: analyses of two independent genomic datasets

Fig. 4

Likely BRCA1 and BRCA2 reversion mutations found in the cohort. For each gene, the boxes in the middle indicate protein and domain structures. Numbers below indicate amino acid numbering for the protein. Above the protein structure are the sensitizing mutations and below are candidate reversion mutations. Triangle indicates that the mutation is an indel resulting in frameshift, circle indicates SNV, and rectangle indicates in-frame deletion. Each colour represents a unique sample. The bar below indicates the location of exon 11, the largest exon for BRCA1 and BRCA2

Back to article page