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Fig. 8 | BMC Cancer

Fig. 8

From: MiR-509-3p is oncogenic, targets the tumor suppressor PHLPP2, and functions as a novel tumor adjacent normal tissue based prognostic biomarker in colorectal cancer

Fig. 8

Lateral transfer induced upregulation of miR-509-3p within CCD841CoN induces a metastatic potential within the normal cell line. A An increase in the wound closure ability of miR-509-3p overexpressing CCD841CoN was also observed relative to the empty vector group. This increase was seen for CCD841CoN treated with conditioned media from both HCT116 and SW480 cell lines stably transduced with miR-509-3p (pre-mir). B-C Treatment of CCD841CoN with conditioned media from HCT116 or SW480 stably transduced with miR-509-3p (pre-mir) increased the B migration, and C invasion rates of CCD841CoN, as compared to the empty vector group. *p value < 0.05

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