Fig. 6

MiR-509-3p is overexpressed in the NAT tissue of patients associated with poor prognosis in CRC. Relative expression of miR-509-3p within the A NAT tissue and the tumor tissue in CRC patients exhibiting overall good prognosis versus poor prognosis. The dotted line indicates the median expression of miR-509-3p within the corresponding tissue type. B-E Correlation of the expression of miR-509-3p within the CRC NAT tissue with the clinicopathological characteristics of CRC patients within the study (N = 103) - B Invasion depth, C Distant metastasis, D Tumor stage, and E Tumor size. Expression of miR-509-3p was normalized to the expression of RNU6B. Expression results are shown as -∆CT. Kaplan-Meier curves for F Disease/progression-free survival, and G Overall survival were plotted based on the NAT expression of miR-509-3p in patients with CRC. Expression of miR-509-3p was separated into low and high groups based on the median NAT tissue expression of miR-509-3p. Assessment was performed for a period of 5 years from the date of surgery. H Receiver Operating Characteristic (ROC) curve for NAT tissue expression of miR-509-3p was performed to classify CRC patients showing poor prognosis from good prognosis. *p value < 0.05; **p value < 0.01; ***p value < 0.001