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Fig. 1 | BMC Cancer

Fig. 1

From: MiR-509-3p is oncogenic, targets the tumor suppressor PHLPP2, and functions as a novel tumor adjacent normal tissue based prognostic biomarker in colorectal cancer

Fig. 1

MiR-509-3p is overexpressed in CRC and correlates with an aggressive disease phenotype. A Real-time PCR-based expression analysis of miR-509-3p in CRC tumor and NAT tissues in 103 patients. B-F Correlation of the expression of miR-509-3p within the CRC tumor tissue with the clinicopathological characteristics of CRC patients within the study (N = 103) - B Tumor Invasion Depth, C Lymph Node Metastasis, D Distant Metastasis, E Tumor Stage, and F Tumor Size. For (A-F), expression of miR-509-3p was normalized to the expression of RNU6B. Expression results are shown as -∆CT. F Quantile normalized expression values of miR-509-3p in 20 colonic normal and 54 colorectal tumor samples obtained from the gene expression dataset (ID: GSE30454), publicly deposited within the NCBI’s Gene Expression Omnibus. *p value < 0.05; **p value < 0.01; ***p value < 0.001

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