Table 1 Anamnestic and clinical features of patients selected for this study
ID | Under/Over 40 at the onset | Disease Status | BC Familiarity | BRCA1/2 Mutational status * | Tissue Histology | Menarche Age | Pregnancies | Other Features |
|---|---|---|---|---|---|---|---|---|
P1 | OVER | breast cancer | no | Wt | nr | nr | nr | nr |
P2 | UNDER | breast cancer | yes | Wt | luminal A | 12 | 1 | oral contraceptives |
P3 | OVER | LABC | yes | Wt | Her2 related | 13 | 0 | oral contraceptives |
P4 | OVER | LABC | no | Wt | TNBC | 11 | 3 | smoke |
P5 | UNDER | breast cancer | yes | Wt | luminal A | 11 | 2 | nr |
P6 | OVER | breast cancer | yes | Wt | luminal A | 11 | 1 | smoke, obesity, ovarian stimulation |
P7 | OVER | breast cancer | yes | Wt | nr | 11 | 3 | smoke, oral contraceptives |
P8 | UNDER | LABC | yes | Wt | TNBC | 14 | 3 | smoke |
P9 | UNDER | breast cancer | Yes | BRCA1 | TNBC | 12 | 3 | nr |
P10 | UNDER | breast cancer | yes | Wt | luminal A | 9 | 0 | oral contraceptives |
P11 | UNDER | breast cancer | no | Wt | nr | 11 | 2 | oral contraceptives |
P12 | UNDER | breast cancer | yes | Wt | luminal A | 9 | 1 | nr |
P13 | OVER | breast cancer | yes | Wt | nr | 11 | 1 | ovarian stimulation |
P14 | OVER | LABC | yes | Wt | nr | 14 | 3 | nr |
P15 | UNDER | breast cancer | Yes | BRCA2 | luminal A | 16 | 1 | oral contraceptives, smoke |
P16 | UNDER | breast cancer | yes | Wt | luminal A | 10 | 3 | nr |
P17 | UNDER | breast cancer | no | Wt | luminal A | 12 | 2 | oral contraceptives, smoke |
P18 | UNDER | breast cancer | no | Wt | Her2 related | 11 | 0 | smoke |
P19 | OVER | LABC | yes | Wt | luminal A | 14 | nr | nr |
P20 | UNDER | breast cancer | no | Wt | luminal B | 12 | 1 | oral contraceptives |
P21 | UNDER | breast cancer | yes | Wt | luminal B | 13 | 0 | oral contraceptives, smoke |
P22 | OVER | LABC | yes | Wt | nr | 12 | 2 | smoke |
P23 | UNDER | breast cancer | yes | Wt | nr | 13 | 2 | nr |
P24 | OVER | breast cancer | yes | Wt | nr | 11 | 2 (1 abort.) | nr |
P25 | UNDER | breast cancer | no | Wt | luminal B | 16 | 1 | oral contraceptives, smoke |
P26 | OVER | LABC | yes | Wt | luminal A | 14 | 2 | nr |
P27 | UNDER | breast cancer | Yes | BRCA2 | luminal B | 13 | 2 | oral contraceptives |
P28 | UNDER | breast cancer | yes | Wt | nr | 13 | 0 | nr |
P29 | UNDER | breast cancer | no | Wt | luminal B | 13 | nr | nr |
P30 | UNDER | breast cancer | yes | Wt | Her2 related | 12 | 1 | oral contraceptives |
P31 | UNDER | breast cancer | yes | Wt | nr | 12 | 2 | oral contraceptives |
P32 | UNDER | breast cancer | no | Wt | nr | 12 | 6 | smoke |
P33 | UNDER | breast cancer | yes | Wt | luminal B | 14 | 2 | ovarian stimulation |
P34 | UNDER | breast cancer | no | Wt | luminal B | 13 | 1 | nr |