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Table 4 Fatigue and genetic characteristics

From: Fatigue in breast cancer patients on chemotherapy: a cross-sectional study exploring clinical, biological, and genetic factors

Characteristic (n = 67) Mean (SD) Mean rank p-value
ABCB1 rs1045642
 CC (n = 11) 36.36 (26.80) 30.45 0.572
 CT (n = 27) 34.29 (34.29) 35.87
 TT (n = 27) 38.68 (32.67) 31.17
COMT rs4680
 VV (n = 18) 42.59 (35.80) 33.06 0.814
 VM (n = 32) 28.77 (28.77) 32.45
 MM (n = 16) 47.92 (36.00) 36.09
COMT rs4680 (VV & VM) vs MM
 MM (n = 16) 47.92 (36.00) 36.09 0.527
 VV & VM (n = 50) 40.67 (31.15) 32.67
OPRM1 rs1799971
 AA (n = 52) 43.16 (31.40) 34.07 0.637
 AG (n = 14) 39.68 (36.39) 31.39
 GG (n = 0)
CLOCK rs1801260
 TT (n = 24) 42.59 (33.20) 28.71 0.933
 TC (n = 32) 43.75 (30.26) 28.34
 CC (n = 0)
PER2 rs934945
 GG (n = 40) 37.78 (32.79) 30.69 0.318
 GA (n = 23) 48.79 (30.47) 37.61
 AA (n = 3) 55.56 (38.49) 39.50
PER2 rs934945 (GG & GA) vs AA
 GG & GA (n = 63) 41.80 (32.16) 33.21 0.572
 AA (n = 3) 55.56 (38.49) 39.50
PER2 rs934945 GG vs (GA & AA)
 GA & AA (n = 26) 30.67 (30.67) 37.83 0.132
 GG (n = 40) 32.79 (32.79) 30.69
CRY2 rs10838524
 GG (n = 22) 44.44 (31.80) 35.18 0.564
 AG (n = 31) 44.09 (32.26) 34.39
 AA (n = 13) 35.04 (34.50) 28.54
CRY2 rs10838524 (GG & GA) vs AA
 AA (n = 13) 35.04 (34.50) 28.54 0.289
 GG & GA (n = 53) 44.23 (31.76) 34.72
DRD2 rs6277
 CC (n = 9) 59.26 (31.43) 40.72 0.128
 CT (n = 24) 42.59 (31.03) 31.67
 TT (n = 28) 34.52 (31.77) 27.30
DRD2 rs6277 (CC & CT) vs TT
 TT (n = 28) 34.52 (31.77) 27.30 0.126
 CC & CT (n = 33) 47.14 (31.55) 34.14