Table 3 Results of GO and KEGG pathways enrichment analysis of downregulated genes
From: A2M is a potential core gene in intrahepatic cholangiocarcinoma
Category | Term | Description | Count | FDR |
|---|---|---|---|---|
BP term | GO:0055114 | Oxidation-reduction process | 23 | 3.10E-08 |
BP term | GO:0010951 | Negative regulation of endopeptidase activity | 10 | 4.37E-05 |
BP term | GO:0008152 | Metabolic process | 10 | 2.83E-04 |
CC term | GO:0070062 | Extracellular exosome | 62 | 1.23E-18 |
CC term | GO:0072562 | Blood microparticle | 17 | 1.20E-13 |
CC term | GO:0005739 | Mitochondrion | 28 | 1.51E-06 |
CC term | GO:0005615 | Extracellular space | 28 | 1.54E-06 |
CC term | GO:0005576 | Extracellular region | 28 | 4.39E-05 |
CC term | GO:0005759 | Mitochondrial matrix | 12 | 1.10E-04 |
MF term | GO:0005102 | Receptor binding | 14 | 1.94E-04 |
KEGG pathway | hsa01100 | Metabolic pathways | 44 | 1.04E-11 |
KEGG pathway | hsa00071 | Fatty acid degradation | 11 | 1.47E-09 |
KEGG pathway | hsa04610 | Complement and coagulation cascades | 11 | 1.78E-07 |
KEGG pathway | hsa01130 | Biosynthesis of antibiotics | 16 | 3.55E-07 |
KEGG pathway | hsa04146 | Peroxisome | 10 | 7.44E-06 |
KEGG pathway | hsa01200 | Carbon metabolism | 10 | 8.53E-05 |