Table 1 Genome-wide association studies of total and 17 site-specific cancers
From: Blood pressure and risk of cancer: a Mendelian randomization study
Outcome | No. of SNPs used (systolic/diastolic) | Total sample size | No. of cases | No. of non-cases | ||||
|---|---|---|---|---|---|---|---|---|
UK Biobank | GERA | Total | UK Biobank | GERA | Total | |||
Total cancer | 272/267 | 405243 | 37387 | - | - | 367856 | - | - |
Bladder | 270/267 | 412592 | 1550 | 692 | 2242 | 359825 | 50525 | 410350 |
Breast | 269/266 | 237537 | 13903 | 3978 | 17881 | 189855 | 29801 | 219656 |
Cervix | 270/267 | 226219 | 5998 | 565 | 6563 | 189855 | 29801 | 219656 |
Colon | 270/267 | 414143 | 2897 | 896 | 3793 | 359825 | 50525 | 410350 |
Endometrium | 270/267 | 221693 | 1414 | 623 | 2037 | 189855 | 29801 | 219656 |
Esophagus/stomach | 270/267 | 411441 | 929 | 162 | 1091 | 359825 | 50525 | 410350 |
Kidney | 270/267 | 411688 | 1021 | 317 | 1338 | 359825 | 50525 | 410350 |
Lymphocytic Leukemia | 270/267 | 411202 | 594 | 258 | 852 | 359825 | 50525 | 410350 |
Lung | 270/267 | 412835 | 1728 | 757 | 2485 | 359825 | 50525 | 410350 |
Melanoma | 270/267 | 417127 | 4271 | 2506 | 6777 | 359825 | 50525 | 410350 |
Non-Hodgkin's Lymphoma | 270/267 | 412750 | 1760 | 640 | 2400 | 359825 | 50525 | 410350 |
Oral cavity/pharyngeal | 270/267 | 411573 | 930 | 293 | 1223 | 359825 | 50525 | 410350 |
Ovary | 270/267 | 220915 | 1006 | 253 | 1259 | 189855 | 29801 | 219656 |
Pancreas | 270/266 | 411013 | 471 | 192 | 663 | 359825 | 50525 | 410350 |
Prostate | 268/267 | 201486 | 7441 | 3351 | 10792 | 169970 | 20724 | 190694 |
Rectum | 270/267 | 412441 | 1808 | 283 | 2091 | 359825 | 50525 | 410350 |
Thyroid | 270/267 | 411112 | 527 | 235 | 762 | 359825 | 50525 | 410350 |