Table 8 Univariate analysis and multivariate analysis for progression predictive factors of PDAC patients at TNM stage I to II in TCGA

Age (≥ 66 vs. <  66)

0.98 (0.641-1.498)

0.926

–

–

Gender (Male vs. Female)

1.106 (0.725-1.687)

0.641

–

–

T stage (T3-T4 vs. T1-T2)

1.300 (0.668-2.528)

0.440

–

–

N stage (N2 vs. N1)

1.283 (0.770-2.137)

0.338

–

–

TNM Stage (II vs. I)

1.179 (0.512-2.719)

0.699

–

–

Grade (G2 vs. G1)

0.878 (0.464-1.662)

0.690

0.765 (0.375-1.558)

0.460

 (G3 vs. G1)

1.372 (0.696-2.706)

0.361

1.492 (0.712-3.127)

0.289

 (G4 vs. G1)

8.307 (1.023-67.451)

0.048^*

5.827 (0.683-49.722)

0.107

Surgery type (Whipple and TP vs. DP and other type)

1.331 (0.743-2.385)

0.336

–

–

Residual tumour (R1-R2 vs R0)

2.200 (1.399-3.461)

0.001^*

2.723 (1.678-4.419)

< 0.001^*

History of diabetes (Yes vs. No)

0.647 (0.36-1.161)

0.144

–

–

SGLT-1 (SLC5A1) (High vs. Low)

0.510 (0.322-0.809)

0.004^*

0.454 (0.280-0.737)

0.001^*

MAP-17 (PDZK1IP1) (High vs. Low)

0.971 (0.627-1.502)

0.894