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Table 5 Univariate analysis and multivariate analysis for survival predictive factors of PDAC in TCGA

From: The expression and survival significance of sodium glucose transporters in pancreatic cancer

Variables

Univariable

Multivariable

HR (95%CI)

P

HR (95%CI)

P

Age (≥ 66 vs. <  66)

0.971 (0.629-1.498)

0.893

–

–

Gender (Male vs. Female)

0.852 (0.552-1.316)

0.471

–

–

T stage (T3-T4 vs. T1-T2)

1.165 (0.580-2.339)

0.669

–

–

N stage (N2 vs. N1)

1.376 (0.805-2.349)

0.243

–

–

TNM Stage (II vs. I)

0.962 (0.416-2.223)

0.928

–

–

 (III vs. I)

0.489 (0.059-4.074)

0.508

–

–

 (IV vs. I)

1.279 (0.255-6.412)

0.765

–

–

Grade (G2 vs. G1)

1.078 (0.540-2.152)

0.831

–

–

 (G3 vs. G1)

1.432 (0.691-2.971)

0.334

–

–

 (G4 vs. G1)

1.228 (0.156-9.676)

0.845

–

–

Surgery type (Whipple and TP vs. DP and other type)

1.839 (0.960-3.524)

0.066

1.643 (0.813-3.321)

0.167

Residual tumour (R1-R2 vs R0)

1.765 (1.104-2.822)

0.018*

1.825 (1.136-2.931)

0.013*

History of diabetes (Yes vs. No)

0.981 (0.557-1.728)

0.947

–

–

SGLT-1 (SLC5A1) (High vs. Low)

0.593 (0.369-0.953)

0.031*

0.593 (0.362-0.970)

0.038*

MAP-17 (PDZK1IP1) (High vs. Low)

1.394 (0.867-2.243)

0.170

  
  1. TP Total Pancreatectomy, DP Distal Pancreatectomy
  2. * Statistical significance