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Table 3 Univariate and multivariate analyses for predictive factors of PDAC survival

From: The expression and survival significance of sodium glucose transporters in pancreatic cancer

Variables

Univariable

Multivariable

HR (95% CI)

P

HR (95% CI)

P

Age (years)

 

0.176

 

0.103

 < 64

Ref

 

Ref

 

 ≥ 64

1.578 (0.815–3.058)

 

–

 

Sex

 

0.993

 

0.269

 Female

Ref

 

Ref

 

 Male

0.997 (0.493–2.015)

 

–

 

TNM stage

 

0.074

 

0.062

 I

Ref

 

Ref

 

 II

2.591 (0.830–8.087)

0.101

3.111 (0.979–9.886)

0.054

 III

3.080 (1.172–8.089)

0.022*

3.145 (1.198–8.260)

0.020*

Grade

 

0.053

 

0.034*

 I

Ref

 

Ref

 

 II

1.843 (0.883–3.874)

0.104

2.257 (1.044–4.882)

0.039*

 III

2.091 (0.909–4.811)

0.083

2.881 (1.190–6.977)

0.019*

SMV/SMA invasion

 

0.385

 

0.747

 No

Ref

 

Ref

 

 Yes

1.331 (0.699–2.536)

 

–

 

History of diabetes

 

0.637

 

0.550

 No

Ref

 

Ref

 

 Yes

1.209 (0.549–2.666)

 

–

 

SGLT-1

 

0.051

 

0.015*

 Low

Ref

 

Ref

 

 High

0.508 (0.257–1.004)

 

0.419 (0.207–0.846)

 
  1. SMV Superior mesenteric vein, SMA Superior mesenteric artery, HR Hazard ratio, CI Confidence interval
  2. *Statistical significance
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