Fig. 5

Potential reason for the survival significance of SGLT-1 in PDAC. A Expression level of SGLT-1 across different grades of pathological differentiation in IHC. B Expression level of SGLT-1 across different TNM stages in IHC. C The correlation between the expression level of GLUT-1 and SGLT-1 in IHC. D Statistical analysis of the mRNA level of MAP17 (PDZK1IP1) between tumour and normal tissues in pancreatic cancer in the GEO database (GEO series 15471, 28735 and 62165). E Relationships between the mRNA levels of SGLT-1 (SLC5A1) and MAP17 (PDZK1IP1) in pancreatic cancer on the basis of the GEO database in the same series. F Kaplan–Meier analysis of OS for patients with high vs. low MAP17 (PDZK1IP1) mRNA expression based on data downloaded from TCGA. G Kaplan–Meier analysis of PFS for patients with high vs. low MAP17 (PDZK1IP1) mRNA expression based on data downloaded from TCGA. Pearson’s correlations were used to estimate the correlation efficiency and statistical significance (^** for P < 0.01, ^*** for P < 0.001, ^**** for P < 0.0001, ns: not significant, error bar: standard deviation)