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Fig. 6 | BMC Cancer

Fig. 6

From: Oral administration of cystine and theanine attenuates 5-fluorouracil-induced intestinal mucositis and diarrhea by suppressing both glutathione level decrease and ROS production in the small intestine of mucositis mouse model

Fig. 6

Influence of CT on the antitumor efficacy of antitumor drug in a tumor-bearing mouse model. CT26 murine colon cancer cells (1 × 106) were subcutaneously transplanted into male BALB/c mice. From Day 8 post transplantation, mice were orally administered CT (280 mg/kg) or methyl cellulose (the vehicle for CT) once daily for 10 days. The mice received 5-FU (150 mg / kg, i.p.) on day 10 after transplantation. The data is presented as the mean ± SEM of 6 mice. CT26 group vs CT26 + 5-FU and CT26 group vs CT26 + 5FU + CT group: ** < 0.01. CT26 + 5-FU group vs CT26 + 5-FU + CT group: No significant difference. (Dunnet’s multiple composition test)

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