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Fig. 2 | BMC Cancer

Fig. 2

From: Oral administration of cystine and theanine attenuates 5-fluorouracil-induced intestinal mucositis and diarrhea by suppressing both glutathione level decrease and ROS production in the small intestine of mucositis mouse model

Fig. 2

Small intestinal villus-protecting effects of CT in 5-FU-induced small intestinal mucositis model. a Typical small intestinal villus tissue in each group. The tissue was excised on day 6 after 5-FU administration and subjected to hematoxylin-eosin staining. b Time-course changes in small intestinal villus length (from the top of villus to the villus-crypt junction). H/E-stained small intestinal villus tissue was observed under a light microscope. Ten villi with relatively normal morphology were selected per animal, the villus length was measured, and the mean was regarded as individual mice data. Values are expressed as the mean ± SEM. N = 5–6. *p < 0.05 vs 5-FU by the two-tailed Student’s t-test

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