From: The blood level of thioredoxin 1 as a supporting biomarker in the detection of breast cancer
Variable | BI-RADS | Trx1 (95% CI) | No. | % |
Breast cancer patientsa | 0 | 23.22 (19.89 to 26.55) | 29 | 28.2 |
(n = 103) | 1 | 22.02 (NA) | 1 | 1 |
2 | 10.26 (NA) | 1 | 1 | |
3 | 22.38 (NA) | 1 | 1 | |
4 | 21.84 (20.14 to 23.53) | 52 | 50.5 | |
5 | 20.43 (17.87 to 22.99) | 19 | 18.4 | |
6 | 0(NA) | 0 | 0 | |
Women without cancerb | 0 | 2.53(NA) | 1 | 2.4 |
(n = 42) | 1 | 6.16(4.49 to 7.82) | 32 | 76.2 |
2 | 6.10(2.34 to 9.87) | 8 | 19 | |
3 | 3.61(NA) | 1 | 2.4 | |
Variable | Confirmed BC patients | Women without cancer | Â | |
Mammography | BI-RADS 4-5 | 71 | 0 | Â |
BI-RADS 0-3 | 32 | 42 | Â | |
Total | 103 | 42 | Â | |
Trx1 | ≥ 11.4 ng/ml | 100 | 5 |  |
<  11.4 ng/ml | 3 | 37 |  | |
Total | 103 | 42 | Â | |
Mammography + Trx1c | Positive | 101 | 0 | Â |
Negative | 2 | 42 | Â | |
Total | 103 | 42 | Â | |
Variable | Sensitivity(%) | Specificity(%)d | Â | |
Mammography | 68.93 | 100.00 | Â | |
Trx1 | 97.09 | 88.10 | Â | |
Mammography + Trx1 | 98.06 | 100.00 | Â |