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Table 2 Comparison of MLL-PTD and WT1 at the initial diagnosed and peri-transplant patients

From: Monitoring of post-transplant MLL-PTD as minimal residual disease can predict relapse after allogeneic HSCT in patients with acute myeloid leukemia and myelodysplastic syndrome

 

MLL-PTD > 0.08% (n/total tests, positive rate)

Median level of MLL-PTD > 0.08% (range, %)

Median level of MLL-PTD (range, %)

WT1 > 0.6% (n/total tests)

Median level of WT1 > 0.6% (range, %)

P value (MLL-PTD+ vs. WT1+)

The initial diagnosis

48/48(100%)

30.30 (1.20-631.00)

30.30 (1.20-631.00)

44/47(93.6%)

26.20 (0.82-83.20)

0.233

Pre-transplantation

37/48(68.8%)

6.10 (0.10-414.10)

1.70 (0.017-414.10)

28/47(59.6%)

6.20 (0.88-53.50)

0.351

Post-transplantation

  + 1 month

8/43(18.6%)

0.115 (0.083-0.73)

0.046 (0.01-0.73)

1/46(2.2%)

0.82

0.027

  + 2 month

12/44(27.3%)

0.21 (0.09-0.82)

0.047 (0-0.82)

3/45(6.7%)

0.86 (0.74-2.4)

0.009

  + 3 montha

13/45(28.9%)

0.28 (0.086-104.70)

0.05 (0-104.70)

6/46(13.0%)

1.50 (0.75-32.70)

0.063

  + 4.5 montha

8/38(21.1%)

1.30 (0.082-55.30)

0.0515 (0-55.30)

9/39(23.1%)

3.90 (0.81-44.10)

0.524

  + 6 montha

11/39(28.2%)

1.40 (0.096-101.30)

0.053 (0.015-101.30)

12/39(30.8%)

1.30 (0.60-80.90)

0.500

  + 9 montha

5/27(18.5%)

0.09 (0.08-0.11)

0.0445 (0-1.00)

3/34(8.8%)

0.71 (0.63-0.74)

0.231

  + 12 month

1/30(3.3%)

0.45

0.049 (0-0.45)

5/32(15.6%)

0.88 (0.72-1.00)

0.113

  1. aPatients underwent hematological relapse at that time point