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Table 1 Characteristics of the 52 analyzed patients

From: High prevalence of anterior pituitary deficiencies after cranial radiation therapy for skull base meningiomas

Factor

Value

Total number of patients

52

Age at diagnosis (years)

56.2 +/− 14.1

Sex

 Female

42 (80.8%)

 Male

10 (19.2%)

Post menopause women

26 (50%)

BMI (kg/m2)

 < 18,5

3 (5.8%)

 18,5–24,9

38 (73%)

 > 25

6 (11.5%)

 > 30

5 (9.7%)

Symptomatic disease manifestation

51 (98.1%)

Localization of skull base meningiomas:

 Anterior

21/52 (40.4%)

 Medial

31/52 (59.6%)

Surgical resection before radiotherapy:

18 (34.6%)

Gross total resection

3 (16.7%)

Subtotal resection

14 (77.8%)

Biopsy

1 (5.5%)

WHO tumor grade

 I

17 (32.7%)

 II

1 (1.9%)

Size of meningioma (mm)

27.8 +/− 13.9

Radiation therapy characteristics

 IMRT

52 (100%)

Energy

 10X

10 (19.2%)

 6X

42 (80.8%)

Overall treatment time (days)

42.3 +/− 5.3

Number of fractions

28.5 +/− 1.8

Total dose (Gy)

54.1 +/− 1.6

Dose to HP axis (Gy)

47 +/−  9.4

  1. Results are presented as mean+/− standard deviation or by frequency and percentage.
  2. Abbreviations: BMI Body Mass Index, WHO World Health Organization, IMRT Intensity Modulated Radiation Therapy, Gy Gray