Factors | Percentiles | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
0.05 | 0.15 | 0.25 | 0.35 | 0.45 | 0.55 | 0.65 | 0.75 | 0.85 | 0.95 | |
Constant | 0.879 (0.065) | 9.246 (0.787) | 5.892 (0.725) | 2.208 (0.219) | 5.293 (0.520) | 8.165 (0.954) | 4.873 (0.549) | 7.216 (0.773) | 6.928 (0.761) | 12.269 (0.970) |
TGF-β1 | 246.281 (4.088**) | 394.203 (7.519**) | 481.854 (13.296**) | 508.789 (11.315**) | 575.917 (12.679**) | 593.743 (15.561**) | 629.329 (15.912**) | 637.585 (15.305**) | 624.232 (15.366**) | 838.401 (14.859**) |
Erk1/2 | 120.037 (1.417) | 17.122 (0.232) | 37.736 (0.740) | 35.942 (0.568) | 5.311 (0.083) | 8.878 (0.165) | 7.135 (0.128) | −19.103 (−0.326) | 10.072 (0.176) | −28.314 (− 0.357) |
Smad2/3 | −74.443 (1.113) | −16.223 (− 0.223) | −66.575 (− 1.322) | 2.282 (0.037) | 35.236 (0.558) | 22.914 (0.432) | 56.750 (1.033) | 98.069 (1.940) | 92.868 (1.859) | 9.671 (0.123) |
AKT | 76.114 (1.115) | 23.651 (0.364) | −4.522 (− 0.101) | −37.059 (− 0.665) | −33.669 (− 0.598) | −47.726 (− 1.009) | − 45.340 (− 0.924) | −46.166 (− 0.893) | 1.183 (0.023) | 6.457 (0.092) |
PI3K | −59.305 (− 0.800) | −61.242 (− 0.950) | −57.044 (− 1.280) | −26.049 (− 0.471) | −34.215 (− 0.613) | −11.215 (− 0.239) | 16.930 (0.348) | 9.701 (0.189) | −4.563 (− 0.091) | 23.487 (0.338) |
p38 MAPK | −69.315 (− 1.103) | 4.674 (0.086) | − 17.941 (− 0.475) | −20.672 (− 0.441) | 2.370 (0.050) | 37.668 (0.947) | 45.589 (1.106) | 22.639 (0.521) | −44.900 (− 1.060) | − 2.834 (− 0.048) |
JNK2 | 34.819 (0.475) | −3.160 (− 0.050) | 19.572 (0.444) | 18.803 (0.344) | − 20.441 (− 0.370) | −72.192 (− 1.556) | −65.744 (− 1.299) | −94.286 (− 1.861) | − 88.809 (− 1.850) | −130.496 (− 1.902) |