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Table 5 Univariate and multivariate Cox regression for overall survival in ICC patients after curative resection after PSM

From: Prognostic value and predication model of microvascular invasion in patients with intrahepatic cholangiocarcinoma: a multicenter study from China

Variables

Univariate

Multivariate

HR

95% CI

P-value

HR

95% CI

P-value

Age, year

1.218

0.841–1.764

0.297

   

Sex, male vs female

1.006

0.703–1.440

0.973

   

Hepatitis, no vs yes

0.879

0.602–1.283

0.505

   

Child-Pugh grade,

Grade A vs Grade B

2.187

1.407–3.399

0.001

2.098

1.344–3.274

0.001

Total bilirubin, μmol/L

< 20 vs ≥20

1.325

0.927–1.895

0.123

   

CA199, U/mL

< 200 vs ≥200

0.814

0.53–1.249

0.346

   

CEA, μg/L < 5 vs ≥5

1.431

0.991–2.066

0.056

   

Blood loss, ml

< 800 vs ≥800

1.000

0.667–1.498

0.999

   

Blood transfusion,

no vs yes

0.798

0.477–1.333

0.388

   

Tumor diameter, cm

≤5 vs > 5

1.529

1.006–2.323

0.047

   

Tumor number

single vs multiple

1.215

0.848–1.740

0.289

   

Surgical margin width, cm < 1 vs ≥1

0.940

0.632–1.397

0.759

   

Satellite nodules

no vs yes

1.212

0.847–1.734

0.293

   

Laparoscopy

no vs yes

0.978

0.455–2.100

0.954

   

Differentiation

moderate or high vs poor

0.868

0.577–1.306

0.498

   

Major hepatectomy

no vs yes

1.526

1.014–2.297

0.043

1.423

0.941–2.15

0.094

Hepatolith no vs yes

1.213

0.592–2.486

0.598

   

MVI no vs yes

1.542

1.073–2.217

0.019

1.576

1.096–2.266

0.014

Postoperative hospital stay, day < 15 vs ≥15

0.894

0.624–1.282

0.542

   
  1. Abbreviations: ICC Intrahepatic cholangiocarcinoma, PSM Propensity Score Matching, HR Hazard ratio, CI Confidence interval, CA199 Carbohydrate antigen 199, CEA Carcinoembryonic antigen, MVI Microvascular invasion