Table 4 Univariate and multivariate Cox regression for recurrence-free survival in ICC patients after curative resection before PSM

Age, year

0.879

0.713–1.083

0.227

Sex, male vs female

1.098

0.895–1.347

0.369

Hepatitis, no vs yes

0.946

0.764–1.171

0.610

Child-Pugh grade,

Grade A vs Grade B

1.655

1.335–2.052

< 0.001

Total bilirubin, μmol/L

< 20 vs ≥20

1.523

1.242–1.867

< 0.001

CA199, U/mL

< 200 vs ≥200

0.798

0.614–1.036

0.090

CEA, μg/L < 5 vs ≥5

0.983

0.768–1.257

0.889

Blood loss, ml

< 800 vs ≥800

1.065

0.821–1.382

0.634

Blood transfusion,

no vs yes

0.838

0.622–1.129

0.246

Tumor diameter, cm

≤5 vs > 5

1.481

1.194–1.836

< 0.001

Tumor number

single vs multiple

1.440

1.155–1.796

0.001

Surgical margin width, cm < 1 vs ≥1

0.851

0.682–1.062

0.154

Satellite nodules

no vs yes

1.686

1.357–2.094

< 0.001

Laparoscopy

no vs yes

0.674

0.388–1.173

0.163

Differentiation

moderate or high vs poor

0.785

0.599–1.029

0.080

Major hepatectomy

no vs yes

1.815

1.465–2.249

< 0.001

Hepatolith no vs yes

0.990

0.569–1.722

0.971

MVI no vs yes

1.840

1.392–2.431

< 0.001

Postoperative hospital stay, day < 15 vs ≥15

1.043

0.849–1.281

0.688