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Fig. 3 | BMC Cancer

Fig. 3

From: High efficacy of PD-1 inhibitor after initial failure of PD-L1 inhibitor in Relapsed/Refractory classical Hodgkin Lymphoma

Fig. 3

A Representative image (40× resolution) from patient 2. PD-L1 (green) and 

PD-L1 (pink) expression in CD68+ (red) macrophages, HRS cells, and background cells in primary tumors from patient 2. The cells with large nuclei and at least two nuclear lobes are HRS cells. PD-L1 and PD-L2 are colocalized in HRS cells. PD-L1 protein was expressed on the membrane (green) of HRS cells, TAMs, and background cells. PD-L2 was weakly expressed (pink). Representative image (40× resolution) from patient 5. PD-L2 was highly expressed in HRS cells, TAMs, and other background cells in patient 5 

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