Fig. 5From: pERK-mediated IL8 secretion can enhance the migration, invasion, and cisplatin resistance of CD10-positive oral cancer cellsIL8 secreted by CD10H HN6 cells promoted migration and invasion and restores tumor chemosensitivity. HN6 Mock CD10H, HN6 Oe CD10L, and HN6 Mock CD10L were identified by real-time PCR (A) and Western blot (B). The three groups were compared by transwell assay to explore the ability of migration and invasion (C&D). Cell viability of CD10H and CD10L HN6 cells were valued by CCK8 when treated with cisplatin and/or SB225002 (E).Back to article page