Fig. 6

Downstream target molecular of miR-107 was HMGA2. a Predicted binding sites of miR-107 in HMGA2 3′-UTR. b Plasmid vectors of human HMGA2 3′-UTR or its mutation were transfected into 293 T cells together with miR-107 mimic or NC. Data were expressed as fold change of the luciferase activity over the control from the NC group (mean ± SD, n = 3). Statistical significances were determined using one-way ANOVA followed by Dunnett’s test. ^**P < 0.01, compared with respective controls