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Fig. 5 | BMC Cancer

Fig. 5

From: Exosomal microRNA-107 reverses chemotherapeutic drug resistance of gastric cancer cells through HMGA2/mTOR/P-gp pathway

Fig. 5

The expression levels of miR-107 and HMGA2 mRNA in SGC-7901, MGC-803 and SGC-7901/5-FU cells and exosomes were detected by qPCR. the expression levels of miR-107 (a) and HMGA2 mRNA (b) in SGC-7901, MGC-803 sensitive and SGC-7901/5-FU resistant cells; the expression levels of miR-107 (c) in SGC-7901, MGC-803 sensitive and SGC-7901/5-FU resistant exosomes. mRNA and miRNA levels were determined by qPCR using GAPDH and U6 as the internal control, respectively. Data were expressed as the mean ± SD (n = 3). Statistical significances were determined using one-way ANOVA followed by Dunnett’s test. *P < 0.05, **P < 0.01, compared with SGC-7901 cells/exosomes; ##P < 0.01, compared with MGC-803 cells/exosomes

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