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Table 4 Univariate and multivariate cox regression analyses for overall survival in cervical cancer patients in validation cohort

From: Prognostic value of preoperative peripheral blood mean platelet volume/platelet count ratio (MPV/PC) in patients with resectable cervical cancer

Variables

Univariate analysis

Multivariate analysis

HR (95%CI)

P value

HR (95%CI)

P value

Age

  ≤ 45 years vs. > 45 years

1.48 (0.80–2.72)

0.212

  

Histological grade 0.859

 G1

Ref.

  

 G2

1.27 (0.44–3.68)

0.660

  

 G3

1.10 (0.365–3.32)

0.865

  

Tumor invasion depth

  > 1/2 vs. ≤1/2

1.58 (0.86–2.89)

0.142

  

Tumor size

  > 4 vs. ≤4

2.03 (1.10–3.74)

0.024*

1.29 (0.67–2.52)

0.449

Lymphovascular invasion

 Yes vs. No

2.20 (1.19–4.07)

0.012*

2.63 (1.34–5.13)

0.005*

FIGO stage

 

0.001*

 

< 0.001*

 IA

Ref.

 

Ref.

 

 IB

6.13 (1.42–26.43)

0.015*

7.91 (1.79–34.92)

0.006*

 IIA

13.16 (3.08–56.19)

0.001*

20.43 (4.46–93.65)

< 0.001*

Radiotheropy

 Yes vs. No

1.42 (0.74–2.71)

0.281

  

MPV/PC

  > 0.41 vs. ≤0.41

0.38 (0.21–0.72)

0.003*

0.35 (0.18–0.66)

0.001*

NLR

  > 2.75 vs. ≤2.75

2.04 (1.03–4.06)

0.042*

1.96 (0.98–3.94)

0.058

PLR

  > 128 vs. ≤128

2.02 (1.10–3.71)

0.024*

1.74 (0.92–3.31)

0.090

MLR

  > 0.27 vs. ≤0.27

1.89 (1.00–3.55)

0.049*

1.57 (0.81–3.04)

0.184

  1. MPV/PC mean platelet volume/platelet count, NLR neutrophil lymphocyte ratio, PLR platelet lymphocyte ratio, MLR monocyte lymphocyte ratio