Fig. 6
From: MMP12 knockout prevents weight and muscle loss in tumor-bearing mice
Inhibiting MMP12 in ApcMin/+ Mice Slows Down Weight Loss. A Schematic diagram of the administration process of 17-week-old ApcMin/+ mice. The drugs were given every 2 days (MMP408: 5 mg/kg, 5-FU: 30 mg/kg). The saline group was used as a control. B Percentage of weight gain compared to the basal weight after administration of drugs in ApcMin/+ mice (**P < 0.01, data are shown as means ± SD; n = 5 per group)