Skip to main content

Table 2 Comparison of clinical data among clustered groups

From: Stepwise correlation of TP53 mutations from pancreaticobiliary maljunction to gallbladder carcinoma: a retrospective study

 

TP53 mutation group

Without TP53 mutation group

CNV group

p

(n = 15)

(n = 12)

(n = 7)

 

Age, mean ± SD, years

68.3 ± 10.2

74.3 ± 9.2

76.1 ± 10.9

0.100

Sex, male, n (%)

4 (26.7)

2 (16.7)

3 (42.9)

0.160

Gallstones, n (%)

5 (33.3)

6 (50)

4 (57.1)

0.510

Smoking, n (%)a

1 (10)

2 (16.7)

2 (28.6)

0.610

PBM, n (%)a

6 (60)

2 (20)

0

0.027

Histological type

   

0.130

 pap, n (%)

6 (40)

5 (41.7)

0

 

 tub1, n (%)

7 (46.7)

4 (33.3)

2 (28.6)

 

 tub2, n (%)

2 (13.3)

2 (16.7)

3 (42.9)

 

 poor, n (%)

0

1 (8.3)

2

 

T factor

   

0.410

 T1, n (%)

4 (26.7)

3 (25)

0

 

 T2, n (%)

9 (60)

7 (58.3)

4 (57.1)

 

 T3, n (%)

2 (13.3)

2 (16.7)

3 (42.9)

 

Lymph node metastasis, n (%)

5 (33.3)

2 (16.7)

3 (42.9)

0.440

Number of actionable genes, median (range)

1 (0–1)

0 (0–2)

4 (3–5)

< 0.01

  1. CNV Copy number variation, PBM Pancreaticobiliary maljunction, pap Papillary adenocarcinoma, tub1 well-differentiated tubular adenocarcinoma, tub2 Moderately-differentiated tubular adenocarcinoma, poor Poorly-differentiated adenocarcinoma
  2. aSamples with unknown data were excluded
  3. p values were calculated using chi-square test or one-way distributed analysis