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Table 2 Comparison of clinical data among clustered groups

From: Stepwise correlation of TP53 mutations from pancreaticobiliary maljunction to gallbladder carcinoma: a retrospective study

  TP53 mutation group Without TP53 mutation group CNV group p
(n = 15) (n = 12) (n = 7)  
Age, mean ± SD, years 68.3 ± 10.2 74.3 ± 9.2 76.1 ± 10.9 0.100
Sex, male, n (%) 4 (26.7) 2 (16.7) 3 (42.9) 0.160
Gallstones, n (%) 5 (33.3) 6 (50) 4 (57.1) 0.510
Smoking, n (%)a 1 (10) 2 (16.7) 2 (28.6) 0.610
PBM, n (%)a 6 (60) 2 (20) 0 0.027
Histological type     0.130
 pap, n (%) 6 (40) 5 (41.7) 0  
 tub1, n (%) 7 (46.7) 4 (33.3) 2 (28.6)  
 tub2, n (%) 2 (13.3) 2 (16.7) 3 (42.9)  
 poor, n (%) 0 1 (8.3) 2  
T factor     0.410
 T1, n (%) 4 (26.7) 3 (25) 0  
 T2, n (%) 9 (60) 7 (58.3) 4 (57.1)  
 T3, n (%) 2 (13.3) 2 (16.7) 3 (42.9)  
Lymph node metastasis, n (%) 5 (33.3) 2 (16.7) 3 (42.9) 0.440
Number of actionable genes, median (range) 1 (0–1) 0 (0–2) 4 (3–5) < 0.01
  1. CNV Copy number variation, PBM Pancreaticobiliary maljunction, pap Papillary adenocarcinoma, tub1 well-differentiated tubular adenocarcinoma, tub2 Moderately-differentiated tubular adenocarcinoma, poor Poorly-differentiated adenocarcinoma
  2. aSamples with unknown data were excluded
  3. p values were calculated using chi-square test or one-way distributed analysis