Fig. 3

TP53 mutation in resected tissues. Values of control, PBM (without GBC), non-tumor part of PBM with GBC, and tumor part of PBM with GBC are shown. A The percentages of TP53 mutations in resected tissues are shown. TP53 mutation rate was high in gallbladder carcinoma (GBC) cases with pancreaticobiliary maljunction (PBM), especially in tumor tissues, as compared to PBM patients without carcinoma or control patients with chronic cholecystitis. B The allele frequencies (AFs) of TP53 mutation are shown as boxplots. AFs of TP53 increased from control and PBM to PBM with GBC