Fig. 6From: The neuropeptide calcitonin gene-related peptide links perineural invasion with lymph node metastasis in oral squamous cell carcinomaCGRP increased the wound healing ability of OSCC cells in vitro through itsreceptor calcitonin receptor like receptor (CLR). A CGRP increased the wound healing capacity of OSCC cells, and blockade of CGRP receptor using CLR inhibitor Rimegepant antagonized the effects of CGRP in both HN6 and Cal27 cells. B Knockdown of the CGRP receptor using small interfering RNA antagonized the effects of CGRP in both HN6 and Cal27 cellsBack to article page